Publications are sorted by the BioThema product used or type of assay.

  • Alexander, G., Carlsen, H., and Blomhoff, R. (2003) Strong in vivo activation of NF-kappaB in mouse lenses by classic stressors. Invest Ophthalmol Vis Sci, 44, 2683-2688.
  • Andersson, M. L., and Vennstrom, B. (2000) A choice between transcriptional enhancement and repression by the v-erbA oncoprotein governed by one nucleotide in a thyroid hormone responsive half site. Oncogene, 19, 3563-3569.
  • Bergman, A., Laudon, H., Winblad, B., Lundkvist, J., and Naslund, J. (2004) The extreme C terminus of presenilin 1 is essential for gamma-secretase complex assembly and activity. J Biol Chem, 279, 45564-45572.
  • Bladh, L. G., Liden, J., Dahlman-Wright, K., Reimers, M., Nilsson, S., and Okret, S. (2005) Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-kappaB and activator protein-1 repression. Mol Pharmacol, 67, 815-826.
  • Bleeker, W.K., Munk, M.E., Mackus, W.J.M., van den Brakel, J.H.N., Pluyter, M., Glennie, M.J., van den Winkel, J.G.J. and parren, P.W.H.I. (2007) Estimation of dose requirements for sustained in vivo activity of a therapeutic human anti-CD20 antibody. British Journal of Haematology. 140, 303-312.
  • Cai, W., Rambaud, J., Teboul, M., Masse, I., Benoit, G., Gustafsson, J-Å., Delaunay, F., Laudet, V. and Pongratz, I. (2007) Expression levels of estrogen receptor ß are modulated by components of the molecular clock. Molecular and Cellular Biology. 28, 784-793.
  • Carlsen, H., Moskaug, J. O., Fromm, S. H., and Blomhoff, R. (2002) In vivo imaging of NF-kappa B activity. J Immunol, 168, 1441-1446.
  • Carlsen, H., Myhrstad, M. C., Thoresen, M., Moskaug, J. O., and Blomhoff, R. (2003) Berry intake increases the activity of the gamma-glutamylcysteine synthetase promoter in transgenic reporter mice. J Nutr, 133, 2137-2140.
  • Damdimopoulos, A. E., Miranda-Vizuete, A., Treuter, E., Gustafsson, J. A., and Spyrou, G. (2004) An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling. J Biol Chem, 279, 38721-38729.
  • Damdimopoulos, A.E., Spyrou, G. and Gustafsson, J-Å. (2008) Ligands differentially modify the nuclear mobility of estrogen receptors a and ß.Endocrinology. 149, 339-345.
  • Dufer, M., Krippeit-Drews, P., Lembert, N., Idahl, L. A., and Drews, G. (2001) Diabetogenic effect of cyclosporin A is mediated by interference with mitochondrial function of pancreatic B-cells. Mol Pharmacol, 60, 873-879.
  • Eriksson, J., Karamohamed, S., and Nyren, P. (2001) Method for real-time detection of inorganic pyrophosphatase activity. Anal Biochem, 293, 67-70.
  • Eriksson, J., Nordstrom, T., and Nyren, P. (2003) Method enabling firefly luciferase-based bioluminometric assays at elevated temperatures. Anal Biochem, 314, 158-161.
  • Eriksson, J., Gharizadeh, B., Nordstrom, T., and Nyren, P. (2004) Pyrosequencing trade mark technology at elevated temperature. Electrophoresis, 25, 20-27.
  • Fenne, I.S., Hoang, T., Haugild, M., Vegard Sagen, J., Lien, E.A. and Mellgren, G. (2008) Recruitment of coactivator glucocortid receptor interacting protein 1 to an estrogen receptor transcription complex is regulated by the 3′,5′-cyclic adenosine 5′-monophosphate-dependent protein kinase. Endocrinology. 149(9), 4336-4345.
  • Gharizadeh, B., Kalantari, M., Garcia, C. A., Johansson, B., and Nyren, P. (2001) Typing of human papillomavirus by pyrosequencing. Lab Invest, 81, 673-679.
  • Gradin, K., Toftgard, R., Poellinger, L., and Berghard, A. (1999) Repression of dioxin signal transduction in fibroblasts. Identification Of a putative repressor associated with Arnt. J Biol Chem, 274, 13511-13518.
  • Gradin, K., Whitelaw, M. L., Toftgard, R., Poellinger, L., and Berghard, A. (1994) A tyrosine kinase-dependent pathway regulates ligand-dependent activation of the dioxin receptor in human keratinocytes. J Biol Chem, 269, 23800-23807.
  • Gradin, K., Wilhelmsson, A., Poellinger, L., and Berghard, A. (1993) Lembert, N., and Idahl, L. A. (1998) Alpha-ketoisocaproate is not a true substrate for ATP production by pancreatic beta-cell mitochondria. Diabetes, 47, 339-344.
  • Gao, H., Bryzgalova, G., Hedman, E., Khan, A., Efendic, S., Gustafsson, J. A., and Dahlman-Wright, K. (2006) Long-term administration of estradiol decreases expression of hepatic lipogenic genes and improves insulin sensitivity in ob/ob mice: a possible mechanism is through direct regulation of signal transducer and activator of transcription 3. Mol Endocrinol, 20, 1287-1299.
  • Hoang, T., Fenne, I. S., Cook, C., Borud, B., Bakke, M., Lien, E. A., and Mellgren, G. (2004) cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1. J Biol Chem, 279, 49120-49130.
  • Hoivik, E.A., Aumo, L., Aesoy, R., Lillefosse, H., Lewis, A.E., Perrett, R.M., Stallings, N.R., Hanley, N.A. and Bakke, M. (2008) Deoxyribonucleic acid methylation controls cell type-specific expression of steroidogenic factor 1. Endocrinology. 149, 5599-5609.
  • Jarvis, G. E., Atkinson, B. T., Frampton, J., and Watson, S. P. (2003) Thrombin-induced conversion of fibrinogen to fibrin results in rapid platelet trapping which is not dependent on platelet activation or GPIb. Br J Pharmacol, 138, 574-583.
  • Kilipi, M.K., Atosuo, J.T., and Lilius, E-M.E. (2009) Bacteriolytic activity of the alternative pathway of complement differs kinetically from the classical pathway. Developmental & Comparative Immunology, 33, 10: 1102-1110.
  • Laudon, H., Hansson, E. M., Melen, K., Bergman, A., Farmery, M. R., Winblad, B., Lendahl, U., von Heijne, G., and Naslund, J. (2005) A nine-transmembrane domain topology for presenilin 1. J Biol Chem, 280, 35352-35360.
  • Laudon, H., Karlstrom, H., Mathews, P. M., Farmery, M. R., Gandy, S. E., Lundkvist, J., Lendahl, U., and Naslund, J. (2004) Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis. J Biol Chem, 279, 23925-23932.
  • Laudon, H., Mathews, P. M., Karlstrom, H., Bergman, A., Farmery, M. R., Nixon, R. A., Winblad, B., Gandy, S. E., Lendahl, U., Lundkvist, J., and Naslund, J. (2004) Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein. J Neurochem, 89, 44-53.
  • Lewis, A.E., Rusten, M., Hoivik, E.A., Vikse, E.L., Hansson, M.L, Wallberg, A.E., and Bakke, M. (2008) Phosphorylation of steroidogenic factor 1 is mediated by cyclin-dependent kinase 7. Mol. End.,22, 91-104.
  • Matthews, J., Wihlen, B., Thomsen, J., and Gustafsson, J. A. (2005) Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor alpha to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters. Mol Cell Biol, 25, 5317-5328.
  • Ostberg, T., Svensson, S., Selen, G., Uppenberg, J., Thor, M., Sundbom, M., Sydow-Backman, M., Gustavsson, A. L., and Jendeberg, L. (2004) A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects. J Biol Chem, 279, 41124-41130.
  • Osterlund, T., Everman, D. B., Betz, R. C., Mosca, M., Nothen, M. M., Schwartz, C. E., Zaphiropoulos, P. G., and Toftgard, R. (2004) The FU gene and its possible protein isoforms. BMC Genomics, 5, 49.
  • Peters, A. K., Nijmeijer, S., Gradin, K., Backlund, M., Bergman, A., Poellinger, L., Denison, M. S., and Van den Berg, M. (2006) Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway. Toxicol Sci, 92, 133-142.
  • Rahnama, F., Toftgard, R., and Zaphiropoulos, P. G. (2004) Distinct roles of PTCH2 splice variants in Hedgehog signalling. Biochem J, 378, 325-334.
  • Tujague, M., Thomsen, J. S., Mizuki, K., Sadek, C. M., and Gustafsson, J. A. (2004) The focal adhesion protein vinexin alpha regulates the phosphorylation and activity of estrogen receptor alpha. J Biol Chem, 279, 9255-9263.
  • Qiao, S., Chen, L., Okret, S. and Jondal, M. (2008) Age-related synthesis of glucocorticoids in thymocytes. Experimental Cell Research. 314, 3027-3035.
  • Yu, l., Mohamed, A.J., Simonson O.E., Vargas, l., Blomberg, E.M., Björkstrand, B., Arteaga, H.J., Nore, B.F. and Smith, C.I.E. (2008) Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappa B. Bloodjournal. 111, 4617-4626.
  • Aprath-Husmann, I., Rohrig, K., Gottschling-Zeller, H., Skurk, T., Scriba, D., Birgel, M., and Hauner, H. (2001) Effects of leptin on the differentiation and metabolism of human adipocytes. Int J Obes Relat Metab Disord, 25, 1465-1470.
  • Scriba, D., Aprath-Husmann, I., Blum, W. F., and Hauner, H. (2000) Catecholamines suppress leptin release from in vitro differentiated subcutaneous human adipocytes in primary culture via beta1- and beta2-adrenergic receptors. Eur J Endocrinol, 143, 439-445.
  • Faulds, G., Ryden, M., Ek, I., Wahrenberg, H., and Arner, P. (2003) Mechanisms behind lipolytic catecholamine resistance of subcutaneous fat cells in the polycystic ovarian syndrome. J Clin Endocrinol Metab, 88, 2269-2273.
  • Short, K. R., Nygren, J., Barazzoni, R., Levine, J., and Nair, K. S. (2001) T(3) increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3. Am J Physiol Endocrinol Metab, 280, E761-769.
  • Short, K. R., Nygren, J., Bigelow, M. L., and Nair, K. S. (2004) Effect of short-term prednisone use on blood flow, muscle protein metabolism, and function. J Clin Endocrinol Metab, 89, 6198-6207.
  • Sreekumar, R., Unnikrishnan, J., Fu, A., Nygren, J., Short, K. R., Schimke, J., Barazzoni, R., and Nair, K. S. (2002) Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle. Am J Physiol Endocrinol Metab, 283, E38-43.
  • Sreekumar, R., Unnikrishnan, J., Fu, A., Nygren, J., Short, K. R., Schimke, J., Barazzoni, R., and Nair, K. S. (2002) Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscle. Am J Physiol Endocrinol Metab, 282, E1055-1061.
  • Stump, C. S., Short, K. R., Bigelow, M. L., Schimke, J. M., and Nair, K. S. (2003) Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci U S A, 100, 7996-8001.
  • Hallier-Vanuxeem, D., Prieto, P., Culot, M., Diallo, H., Landry, C., Tähti, H., and Cecchelli, R. (2009) New strategy for alerting central nervous system toxicity: Integration of blood-brain barrier toxicity and permeability in neurotoxicity assessment. Toxicology in vitro. 23, 3:447-453.
  • Jensen, S.E., Hubrechts, P., Klein, B.M., and Haslöv, K.R. (2008) development and validation of an ATP method for rapid estimation of vaible units in lyophilised BCG Danish 1331 vaccine. 36, 5:308-314.
  • Li, D. Q., Lundberg, F., and Ljungh, A. (2000) Binding of von Willebrand factor by coagulase-negative staphylococci. J Med Microbiol, 49, 217-225.
  • Lindmark, T., Kimura, Y., and Artursson, P. (1998) Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells. J Pharmacol Exp Ther, 284, 362-369.
  • Neumann, G., Cornelissen, S., van Breukelen, F., Hunger, S., Lippold, H., Loffhagen, N., Wick, L. Y., and Heipieper, H. J. (2006) Energetics and surface properties of Pseudomonas putida DOT-T1E in a two-phase fermentation system with 1-decanol as second phase. Appl Environ Microbiol, 72, 4232-4238.
  • Olm, E., Jönsson-Videsäter, K., Ribera-Cortada, I., Fernandes, A.P., Eriksson, L.C., Lehmann, S., Rundlöf, A-K., Paul, C., and Björnstedt, M. (2009) Selenite is a potent cytotoxic agent for human primary AML cells. Cancer letters, 282, 1:116-123.
  • Saunders, C., Herbert, P., Rowe, G., Hayward, M., Wilkins, K., Milligan, J., Stenning, M., Seacombe, A., and Prowse, C. (2005) In-vitro evaluation of the PALL Leukotrap Affinity Prion Reduction Filter as a secondary device following primary leucoreduction. Vox Sang, 89, 220-228.
  • Yegutkin, G. G., Mikhailov, A., Samburski, S. S., and Jalkanen, S. (2006) The detection of micromolar pericellular ATP pool on lymphocyte surface by using lymphoid ecto-adenylate kinase as intrinsic ATP sensor. Mol Biol Cell, 17, 3378-3385.
  • Yegutkin, G. G., Samburski, S. S., Jalkanen, S., and Novak, I. (2006) ATP-consuming and ATP-generating enzymes secreted by pancreas. J Biol Chem, 281, 29441-29447.
  • Bufler, G. (2008) Exogenous ethylene inhibits sprout growth in onion bulbs. Annals of Botany. 103, 23-28.
  • Ciz, M., Pavelkova, M., Gallova, L., Kralova, J., Kubala, L. and Lojek, A. (2008) The influence of wine polyphenols on reactive oxygen and nitrogen species production by murine macrophages RAW 264.7. Physiol Res. 57, 393-402.
  • Fransson, U., Rosengren, A. H., Schuit, F. C., Renstrom, E., and Mulder, H. (2006) Anaplerosis via pyruvate carboxylase is required for the fuel-induced rise in the ATP:ADP ratio in rat pancreatic islets. Diabetologia, 49, 1578-1586.
  • Jensen, S.E., Hubrechts, P., Klein, B.M. and Hasløv, K.R. (2007) Development and validation of an ATP method for rapid estimation of viable units in lyophilised BCG Danish 1331 vaccine. Biologicals. 36, 308-314.
  • Lu, M., Hu, L-F., Hu, G., and Bian, J-S. (2008) Hydrogen sulfide protects astrocytes against H2o2-induced neural injury via enhancing glutamate uptake. Free Radical Biology and Medicine. 45, 12:1705-1713.
  • Nahi, H., Sleivanova, G., Lehmann, S., Möllgård, L., Bengtzen, S., Concha, H., Svensson, A., Wiman, K.G., Merup, M. and Paul, C. (2007) Mutated and non-mutaded TP53 as targets in the treatment of leukaemia. British Journal of Haemotology. 141, 445-453.
  • Mercer, A., Rönnholm, H., Holmberg, J., Lundh, H., Heidrich, J., Zachrisson, O., Ossoinak, A., Frisén, J., and Patrone, C. (2004) PACAP promotes neural stem cell proliferation in adult mouse brain. Journal of neuroscience research, 76, 205-215.
  •  Muller, P., Kietz, S., Gustafsson, J. A., and Strom, A. (2002) The anti-estrogenic effect of all-trans-retinoic acid on the breast cancer cell line MCF-7 is dependent on HES-1 expression. J Biol Chem, 277, 28376-28379.
  • Puttonen, K.A., Lehtonen, S., Lampela, P., Männistö, p.T. and Raasmaja, A. (2008) Different viabilities and toxicity types after 6-OHDA and Ara-C exposure evaluated by four assays in five cell lines. Toxicology in vitro. 22, 182-189.
  • Strom, A., Arai, N., Leers, J., and Gustafsson, J. A. (2000) The Hairy and Enhancer of Split homologue-1 (HES-1) mediates the proliferative effect of 17beta-estradiol on breast cancer cell lines. Oncogene, 19, 5951-5953.
  • Thomsen, J. S., Kietz, S., Strom, A., and Gustafsson, J. A. (2004) HES-1, a novel target gene for the aryl hydrocarbon receptor. Mol Pharmacol, 65, 165-171.
  • Tollet, P., Lahuna, O., Ahlgren, R., Mode, A., and Gustafsson, J. A. (1995) CCAAT/enhancer-binding protein-alpha-dependent transactivation of CYP2C12 in rat hepatocytes. Mol Endocrinol, 9, 1771-1781.
  • Toro, J.C., Hoffner, S., Linde, C., Andersson, M., Andersson, J., and Grundström, S. (2006) Enhanced suspectibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides correlates with a reduced fitness phenotype. Microbes infect., 8, 1985-1993.
  • Xie, H-J., Lundgren, S., Broberg, U., Finnström, N., Rane, A. and Hassan, M. (2002) Effect of cyclophosphamide on gene expression of cytochromes P450 and ß-actin in the HL-60 cell line. European Journal of Pharmacology. 449, 197-205.
  • Diaz, L.F., Muñoz, R., Bordel, S., and Villaverde, S. (2007) Inhibitory effects of cathecol accumulation on benzene biodegradation in Pseudonomas putida F1 cultures. Chemosphere. 68, 244-252.
  • Diaz, L.F., Muñoz, R., Bordel, S., and Villaverde, S. (2006) Toluene biodegradation by Pseudonomas putida F1: targeting culture stability in long-term operation.  Biodegradation, 19(2), 197-208.
  • Kodjikian, L., Casoli-Bergeron, E., Malet, F., Janin-Manificat, H., Freney, J., Burillon, C., Colin, J. and Steghens, J-P. (2008) Bacterial adhesion to conventional hydrogel and new silicone-hydrogel contact lens materials. Graefes Arch Clin Exp Ophtalmol . 246, 267-273.
  • Lin, X., Kim, Y-A, Lee, B.L., Söderhäll, K., and Söderhäll, I. (2009) Identification and properties of a receptor for the invertebrate astakine, ivolved in hematopoiesis. Experimental Cell Research. 315, 7: 1171-1180.
  • Lu, M., Hu, L-F., Hu, G., and Bian, J-S. (2008)Hydrogen sulfide protects astrocytes against H2O2induced neural injury via enhancing glutamate uptake. Free Rad. Biol. & Med. 45, 1705-1713.
  • Rud, I., Solem, C., Ruhdal jensen, P., Axelsson, L., and Naterstad, K. (2008)Co-factor engineering in lactobacilli: Effects of uncoupled ATPase activity on metabolic fluxes in Lactobacillus (L.) plantarum and L. sakei.Met. Engineering,10, 207-215.
  • Ziedaite, G., Daugelavicius, R., Bamford, J. K., and Bamford, D. H. (2005) The Holin protein of bacteriophage PRD1 forms a pore for small-molecule and endolysin translocation. J Bacteriol, 187, 5397-5405.
  • Pakostova, E., Mandl, M., Omesova Pokorna, B., Diviskova, E., and Lojek, A. (2012) Cellular ATP Changes in Acidithiobacillus ferrooxidans Cultures Oxidizing Ferrous Iron and Elemental Sulfur. Geomicrobiological Journal, 30, 1-7.
  • Gradin, K., Whitelaw, M.L., Toftgard, R., Poellinger, L. and Berghard, A.. (1994)Nonresponsiveness of normal human fibroblasts to dioxin correlates with the presence of a constitutive xenobiotic response element-binding factor. J Biol Chem, 268, 4061-4068.
  • Hassibi, A., Contag, C., Vlad, M. O., Hafezi, M., Lee, T. H., Davis, R. W., and Pourmand, N. (2005) Bioluminescence regenerative cycle (BRC) system: theoretical considerations for nucleic acid quantification assays. Biophys Chem, 116, 175-185.
  • Gonzales-Alonzo, J.,Olsen, D.B. and Saltin, B. (2002)Erythrocyte and the Regulation of Human Skeletal Muscle Blood Flow and Oxygen Delivery. Circ res, 91, 1046-1055.
  • Jacobson, J., Duchen, M. R., Hothersall, J., Clark, J. B., and Heales, S. J. (2005) Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism. J Neurochem, 95, 388-395.
  • Lundberg, F., Lea, T., and Ljungh, A. (1997) Vitronectin-binding staphylococci enhance surface-associated complement activation. Infect Immun, 65, 897-902.
  • Moskaug, J. O., Carlsen, H., Myhrstad, M. C., and Blomhoff, R. (2005) Polyphenols and glutathione synthesis regulation. Am J Clin Nutr, 81, 277S-283S.