Antibiotic susceptibility as well as antibiotic concentration can be determined using luciferase based assays. Tests are rapid (1.5-2 hours) and measure inhibition of growth or release of extracellular ATP. With slow-growers like mycobacteria susceptibility testing takes 7 days.
Products: 266-311 ATP Biomass Kit HS and 266-112 Microbial ATP Kit HS
Publications: L E Nilsson, S E Hoffner and S Ånséhn Rapid Susceptibility Testing of Mycobacterium tuberculosis by Bioluminescence Assay of Mycobacterial ATP; ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Aug. 1988, p. 1208-1212)